Destruction of a destructor: a new avenue for cancer therapeutics targeting the Wnt pathway.
نویسندگان
چکیده
A new study in Nature has identified a small molecule inhibitor for the oncogenic Wnt/beta-catenin pathway that is responsible for many human cancers. This inhibitor targets an unsuspected cellular enzyme, Tankyrase, which controls the destruction of a beta-catenin destructor.
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عنوان ژورنال:
- Journal of molecular cell biology
دوره 2 2 شماره
صفحات -
تاریخ انتشار 2010